E621 — Monosodium glutamate · page 3

Status in the United States (FDA)

Listed in the FDA inventory “Substances Added to Food”, with the regulations 21 CFR 172.320, 182.1.

Technical effects listed by the FDA: flavor enhancer, nutrient supplement, ph control agent, stabilizer or thickener

The inventory is a partial list, and a listing is not an FDA approval of every use; the regulations set the permitted uses.

U.S. Food and Drug Administration, Substances Added to Food (updated 9/8/2026), public domain · CAS 142-47-2 via Wikidata (CC0)