E421 — Mannitol
E421 (Mannitol) appears in the ingredient lists of 401 products sold in the United States. Function: humectant, stabilizer, sweetener, thickener.
Nutri-Score
337 rated products
Median values
| Calories | 217 kcal |
| Sugars | 0.00 g |
| Saturated fat | 0.00 g |
| Salt | 0.00 g |
Categories
Status in the United States (FDA)
Listed in the FDA inventory “Substances Added to Food”, with the regulations 21 CFR 180.25.
Technical effects listed by the FDA: anticaking agent or free-flow agent, flavor enhancer, flavoring agent or adjuvant, formulation aid, lubricant or release agent, non-nutritive sweetener, solvent or vehicle
The inventory is a partial list, and a listing is not an FDA approval of every use; the regulations set the permitted uses.
U.S. Food and Drug Administration, Substances Added to Food (updated 9/8/2026), public domain · CAS 69-65-8 via Wikidata (CC0)
Products containing it, by country
Products listing this additive in each country edition of Shelfpedia (Open Food Facts data)
Products
401 products, most viewed first · page 1 of 9.
Source: Open Food Facts export of 23 October 2026, ODbL, and USDA FoodData Central, April 2026 release, CC0 · Shelfpedia calculations (medians, distributions).